Subcutaneous immunotherapy with house dust mite extract in Indonesian children with allergic rhinitis and asthma: A double-blind randomized controlled trial.

Respiratory medicine·April 1, 2026·PMID: 41795860

What's New

House dust mite subcutaneous immunotherapy was associated with reduced symptom scores and key immunological markers in Indonesian children with allergic rhinitis and asthma.

Detailed Summary

A double-blind RCT of 41 children with allergic rhinitis (n=20) or allergic rhinitis plus asthma (n=21) evaluated 14 weeks of weekly house dust mite SCIT. Treatment was associated with significant reductions in total IgE, TGF-β1, Combined Symptom Medication Score, and Visual Analogue Scale scores (p<0.05), though no significant differences in treatment effect were observed between the two groups.

Study Population

Indonesian children with house dust mite-related allergic rhinitis or allergic rhinitis plus asthma (n=41)

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