Prevalence and risk factors for nausea and vomiting in breast cancer patients undergoing chemotherapy.

Acta oncologica (Stockholm, Sweden)·April 1, 2026·PMID: 41919779

What's New

Nearly half of breast cancer patients undergoing chemotherapy experienced chemotherapy-induced nausea and vomiting, with younger age and motion sickness history identified as key risk factors.

Detailed Summary

A meta-analysis of 12 studies found the overall prevalence of chemotherapy-induced nausea and vomiting (CINV) in breast cancer patients was 48%. Multivariate analysis identified age ≤45 years (OR 2.36), history of motion sickness (OR 2.05), and ≥3 chemotherapy cycles (OR 2.27) as independently associated risk factors, while anxiety and comorbidities were not significantly associated.

Study Population

Breast cancer patients undergoing chemotherapy, primarily from Asian populations (12 studies)

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