Could impulse oscillometry be an easy and practical test for differential diagnosis in healthy adults and patients with asthma and COPD?

Medicine·April 3, 2026·PMID: 41931355

What's New

Impulse oscillometry parameters differed significantly among healthy adults, asthma patients, and COPD patients, suggesting potential utility in differential diagnosis.

Detailed Summary

A prospective observational study compared impulse oscillometry (IOS) and spirometry results across healthy adults, asthma patients, and COPD patients. COPD patients demonstrated significantly higher R5 Hz resistance compared to both healthy and asthma groups (P=.01), and the resistance difference between 5 and 20 Hz was elevated in COPD but not in asthma relative to healthy adults.

Study Population

Healthy adults without airway disease and patients with asthma or COPD seen at a pulmonology outpatient clinic

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