Does cervical mucus removal before embryo transfer have an effect on cycle outcome in women undergoing ICSI?: A randomised controlled trial.

Human fertility (Cambridge, England)·December 1, 2026·PMID: 41913411

What's New

Cervical mucus removal before embryo transfer did not significantly affect clinical pregnancy rates in women undergoing ICSI cycles.

Detailed Summary

A randomized controlled trial of 183 patients undergoing ICSI compared cervical mucus removal via cotton swab, removal via Pipella cannula, and no removal before embryo transfer. All three groups demonstrated similar clinical pregnancy rates, suggesting the practice did not confer a measurable benefit.

Study Population

Women undergoing ICSI with at least one good quality embryo and adequate endometrial thickness (n=183)

This research is for informational purposes only — discuss with your doctor before making any changes to your care.

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