Omalizumab Dose-Related Efficacy in a Cohort of Children With Severe Food Allergy: OSAFA Observational Study.
What's New
Higher monthly doses of omalizumab were associated with greater food desensitization in children with severe food allergy, independent of baseline IgE levels.
Detailed Summary
An observational study of 76 children with severe asthma and severe IgE-mediated food allergy found a significant association between omalizumab dosage and desensitization after 12 months (OR 1.151; 95% CI, 1.066-1.258), while baseline total IgE levels showed no significant effect, suggesting body weight may be a more appropriate dosing parameter than IgE.
Study Population
Children aged 6-18 years with severe asthma and severe allergy to at least one food allergen (n=76; 69.7% male; mean age 12.2 years)
This research is for informational purposes only — discuss with your doctor before making any changes to your care.
Rivvet may earn a referral fee if you book through this link.
Discussion
Loading comments...
Comments are public. Be respectful and remember: this is not medical advice. Do not share personal health information.