Long-term (>10 Years) Outcomes of Laparoscopic Nissen Fundoplication: A Systematic Review and Meta-Analysis.
What's New
Laparoscopic Nissen fundoplication was associated with durable GERD symptom relief beyond 10 years, with 87% patient satisfaction.
Detailed Summary
A systematic review and meta-analysis of 12 studies (n=1,334) with a mean follow-up of 13.1 years found that heartburn decreased from 94.2% to 33.7%, regurgitation from 68.7% to 13.4%, and esophagitis from 61.7% to 7.4% after laparoscopic Nissen fundoplication. However, gas-bloating and dysphagia were reported in 53% and 26% of patients, respectively, and 24% resumed proton pump inhibitor use.
Study Population
adults with gastroesophageal reflux disease who underwent laparoscopic Nissen fundoplication (n=1,334 across 12 studies)
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