Factors associated with fatigue in patients with systemic lupus erythematosus in an outpatient tertiary care setting: a cross-sectional cohort study.
What's New
Organ damage accrual and higher BMI were associated with clinically significant fatigue in lupus patients, while disease activity was not.
Detailed Summary
A cross-sectional study of 183 SLE outpatients at a tertiary care center found that those with clinically significant fatigue (FSS ≥4) had higher organ damage scores (SLICC/ACR DI 1.9 vs 1.1, p=0.008) and higher BMI (29.6 vs 27.6 kg/m², p=0.03), while disease activity as measured by SELENA-SLEDAI was not significantly associated with fatigue.
Study Population
183 outpatient adults with systemic lupus erythematosus, predominantly from ethnic minority backgrounds, at a tertiary care rheumatology clinic
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